Weight Loss

Healthy weight loss

Top tips for healthy weight loss:

To help you find out if you have a healthy body weight, measure your and waist circumference To lose weight, the energy you take in from food must be less than the energy you use – eat less, move more!

Set yourself realistic goals to achieve a healthy weight. Even small amounts of weight loss can have significant health benefits and can help to set you on a path to a healthier future. Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week

Weight loss can reduce your risk of: heart disease, stroke, type 2 diabetes and some cancers.

It can also reduce the risk of:

High blood pressure Angina (heart condition causing chest pain) High blood cholesterol levels Lower back and joint pain Fertility problems BMI and waist circumference

For most adults:

A BMI between 18.5 and 25 is defined as healthy. A BMI of over 25 is defined as overweight. A BMI of over 30 is defined as obese.

Waist-circumferences for which there is an increased risk and high risk of obesity-related health problems:

Increased risk High risk Men ≥94 cm (37 in) ≥102 cm (40 in) Women ≥80 cm (31.5 in) ≥88 cm (34.5 in)

Sensible weight loss should be seen as an overall lifestyle change which involves eating a healthy balanced diet and doing plenty of physical activity.

Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week. This way, the weight is more likely to stay off. This rate of weight loss is based on using up 600 kcal per day more than you take in. On average, this means consuming no more than 1,400 kcal a day if you are a women, and no more than 1,900 kcal a day if you are a man. The amount of weight you lose will depend on how much weight you need to lose and how active you are.

Further Information

Further information can be found on the manufacturers

Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Orlistat.

The majority of unwanted effects related to the use of Orlistat result from its local action in your digestive system. These symptoms are generally mild, occur at the beginning of treatment and are particularly experienced after meals containing high levels of fat. Normally, these symptoms disappear if you continue treatment and keep to your recommended diet.

Very common (may affect more than 1 in 10 people):

headache abdominal pain/discomfort urgent or increased need to open the bowels flatulence (wind) with or without discharge oily discharge, oily or fatty stools liquid stools low blood sugar levels (experienced by some people with type 2 diabetes) upper respiratory infections flu (influenza)

These conditions are also caused by orlistat which includes orlistat-related pain, gas, itching, skin rash, swelling, dizziness, and sometimes experiencing blurred vision. be careful use sun sensitivity Ilistat doses ( Denise H et al., 2017 ) orlistat ( Keflex ( 2015 ) ) or other weight loss medicines to make Orlistat work better Be careful before continuing treatment if you have orlistat-related symptoms.

If you are taking any other medicines (see above), you should stop taking Orlistat and speak to your pharmacist or doctor before taking any new medicines or starting new treatments.

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Generic Orlistat

Orlistat is available as brand-name medicine a drug used for the treatment of or weight loss in adults.

As medicine is expensive, orlistat is not available over the counter, or your doctor may have prescribed it to you under most circumstances, you are asked to pay the full cost of the medicine for 25p of medicine. This price increase is part of a wider health care plan called a Glaxo Wellbeing ( 2014)

There is no generic version of Orlistat.

Orlistat is now available in the UK as a generic medicine under the name Alli.

Uses of Orlistat

Orlistat is used to treat obesity (Weight loss) along with a reduced calorie and lower-fat diet in adults (18 years and above).

Therapeutic Category

Orlistat: Anti-obesity drugs

How Orlistat works

Orlistat works by attaching to the enzymes in your digestive system (lipases) and preventing them from breaking down some of the fat that you’ve consumed during your meal. The fat that is not digested cannot be absorbed and it is removed by your body.

Common side effects of Orlistat

• flatulence with or without oily spotting
• sudden bowel motions
• fatty or oily stools
• soft stools
• stomach pain
• fecal incontinence
• runny or liquid stools
• more frequent bowel motions
• anxiety
• headache
• respiratory tract infection
• low blood sugar levels
• flu infection
• rectal pain or discomfort
• tooth or gum disorders
• urinary tract infection
• irregular menses
• tiredness

When to consult your doctor

Consult your doctor if you experience:

• severe allergic reactions (severe breathing problems, sweating, rash, itching, swollen face, rapid heartbeat, nausea, vomiting, feeling unwell)
• In case of accidental overdosage or ingestion

Health Tips for Orlistat

• Orlistat works best when combined with a reduced-calorie, balanced diet that contains moderate amounts of fat, carbohydrates, and protein. It is not a license to consume large amounts of high fat foods
• Drink plenty of water throughout the day to stay hydrated, especially if you experience diarrhea as a side effect of Orlistat
• Take Orlistat at the same time each day to maintain a consistent level of the medication in your system
• Orlistat is not recommended for use in pregnant and breast feeding women
• Orlistat can reduce the absorption of fat-soluble vitamins (A, D, E, K) and beta-carotene. To ensure you are getting adequate nutrients, consider taking a multivitamin supplement at least 2 hours before or after taking Orlistat

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Drink at the same time each day to stay hydrated, if you experience flushed or decreased bowel movements, or if symptoms occur that you think are caused by low blood pressure, hormonal changes, or heart problems

Orlistat can also reduce the absorption of fat-soluble vitamins (A, D, E, K) and beta-carotene.

What is Xenical?

Xenical (orlistat) is a prescription medication designed to assist in weight loss. It's typically prescribed to individuals with obesity who haven't achieved their weight loss goals through diet and exercise alone. This drug is approved for use in adults under two specific conditions:

• For those with a Body Mass Index (BMI) of 30 kg/m^2 or higher, indicating obesity.
• For individuals with a BMI of 27 kg/m^2 or higher who also have comorbid weight-related health risks. These risks include conditions like type 2 diabetes mellitus, high blood pressure, or high cholesterol.

Xenical works by interfering with the body's ability to absorb fat from the diet, thereby reducing calorie intake. It is meant to be taken orally, three times a day, with each fat-containing meal. This approach emphasizes the importance of combining the medication with a healthy diet and regular exercise for more effective weight loss.

How Does Xenical Work?

Xenical operates by targeting enzymes in the body known as "lipases." These enzymes are responsible for breaking down dietary fats into smaller components that the body can absorb for energy and storage. When taking Xenical, it inhibits the action of these lipases in the stomach and intestine. This inhibition prevents the complete breakdown and absorption of some fats, leading to their elimination through bowel movements instead of being stored in the body. Consequently, this process contributes to weight loss over time.

An important aspect of Xenical's mechanism is its impact on the absorption of fat-soluble vitamins. Since it reduces fat absorption, it can also reduce the intake of vitamins that are typically absorbed alongside fats. Therefore, patients using Xenical are advised to supplement their diet with a multivitamin containing fat-soluble vitamins. To ensure proper vitamin absorption, the multivitamin should be taken at least two hours before or after taking Xenical. This precaution helps maintain an adequate level of essential nutrients while using the medication.

What to Expect

Xenical has been shown to enhance weight loss when used in conjunction with a reduced-calorie diet, more effectively than dieting alone. Research indicates that over 20% of individuals using Xenical, alongside dietary changes, lose at least 5% of their body weight. In some cases, more than 15% of users even experience a loss of at least 10% of their body weight.

However, weight regain can occur once the medication is discontinued. This highlights the importance of continuing a balanced diet and regular exercise regimen even after stopping Xenical. The medication should be viewed as an initial boost in a weight loss journey, rather than a long-term solution. Sustainable weight management relies on ongoing lifestyle changes, including healthy eating and physical activity.

Side Effects

Xenical is known to have common side effects, primarily due to its mechanism of reducing fat absorption. These side effects are mostly related to the presence of unabsorbed fats in the intestines and stools. The typical side effects experienced by users of Xenical include:

• Oily rectal leakage
• Flatulence accompanying bowel movements
• Urgent need to have a bowel movement
• Oily or greasy stools
• Increased frequency of bowel movements
• Bowel incontinence

It's important to note that these side effects are the primary reason for some users discontinuing Xenical. Over 20% of individuals may experience these side effects in the first year of use. However, the incidence of these side effects tends to decrease significantly if the medication is continued into a second year. This reduction over time may be due to the body's adaptation to the drug or adjustments in dietary habits in response to the medication's effects.

Cost of Xenical

At a typical pharmacy, the cost of a 3-month supply of Xenical is about $780. However, there is also an over-the-counter version of Xenical, called. This medication contains a lower dose of orlistat but is less expensive and does not require a prescription.

Prices mentioned in this article are based on average retail price at major box chain pharmacy in the U. S. as of Decmber, 2023.

References:

1. XENICAL - orlistat capsule. Food and Drug Administration. (01/2009). Retrieved July 28, 2023, from https://www.accessdata.fda.govv
2. **Tak, Y. J.

Frequently asked questions

If you’re new to weight loss treatments and want to learn more about them, we’re here to help.

How do weight loss tablets work?

Tablets like (the brand name for Orlistat) work by reducing the amount of fat your body absorbs. Ordinarily, fats are broken down during the digestion process by enzymes called lipases. Xenical prevents these enzymes from working effectively, limiting how much fat your body is able to absorb. The remaining, undigested fat is then excreted.

How do weight loss injections work?

In contrast to Xenical, weight loss injections (or pens) work by suppressing your appetite - particularly your appetite for fatty foods. Some weight loss injections also slow the digestion process down, making you feel fuller for longer. They’re simple to use - check out our for more information.

How effective are weight loss treatments?

Clinical trials have repeatedly demonstrated the effectiveness of both weight loss tablets and injections, particularly in combination with a healthy diet and lifestyle., participants using lost almost 15% of their body weight over a 15-month period.

How do I place an order?

Starting your weight loss journey is simple with IQ Doctor. To begin, click on a product and then hit the 'Start Consultation' button. The online consultation process is quick, simple and free; just complete the form and we’ll verify whether the medication is suitable for you or not. If it is, you can then place your order and receive it the very next day.

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We’re happy to admit that this is a consultation challenge and you should always discuss your health history with our doctors.